Ningetinib Tosylate, CAS 1394820-77-9

Product Description: Ningetinib Tosylate is a potent, orally bioavailable small molecule tyrosine kinase inhibitor (TKI) with IC50s of 6.7, 1.9 and c-Met, VEGFR2 and Axl, respectively.

Applications: Cancer-Kinase/protease

Formula: C38H37FN4O8S

References: [1]Ning Xi, et al. Abstract 1755: CT053PTSA, a novel c-MET and VEGFR2 inhibitor, potently suppresses angiogenesis and tumor growth. Cancer Res 2014;74(19 Suppl):Abstract nr 1755.

CAS Number: 1394820-77-9

Molecular Weight: 728.79

Compound Purity: 99.59

Research Area: Cancer

Solubility: DMSO : 33.33 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C)

Target: c-Met/HGFR;TAM Receptor;VEGFR

• SKU: MEXHY-107145-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-107145-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK