Nitrocefin, CAS 41906-86-9

Product Description: Nitrocefin is a chromogenic β-lactamase substrate that undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics[1][2][3].

Applications: COVID-19-immunoregulation

Formula: C21H16N4O8S2

References: [1]Lee M, et al. A practical synthesis of nitrocefin. J Org Chem. 2005 Jan 7;70(1):367-9./[2]Worthington RJ, et al. Overcoming resistance to β-lactam antibiotics. J Org Chem. 2013 May 3;78(9):4207-13./[3]O'Callaghan CH, et al. Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. Antimicrob Agents Chemother. 1972 Apr;1(4):283-8.

CAS Number: 41906-86-9

Molecular Weight: 516.50

Compound Purity: 92.27

Research Area: Infection

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Antibiotic;Beta-lactamase

• SKU: MEXHY-108913-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108913-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK