NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker)(NX2/2198R), CF740 conjugate, 0.1mg/mL

NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker)(NX2/2198R), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC742198-500
Packaging Unit
500 uL
Manufacturer
Biotium

Availability: loading...
Price is loading...
Description: Expression of NKX2. 2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2. 2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: NX2/2198R

Immunogen: Recombinant human NKX2.2 protein fragment (around aa1-119) (exact sequence is proprietary)

Antibody Reactivity: NKX2.2

Entrez Gene ID: 4821

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)
More Information
SKU BTMBNC742198-500
Manufacturer Biotium
Manufacturer SKU BNC742198-500
Package Unit 500 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Immunohistochemistry
Isotype IgG
Host Rabbit
Conjugate Conjugated, CF740
Product information (PDF) Download
MSDS (PDF) Download