NMS-859, CAS 1449236-96-7

Product Description: NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.

Applications: Cancer-programmed cell death

Formula: C15H12ClN3O3S

References: [1]Magnaghi P, et al. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death. Nat Chem Biol. 2013 Sep;9(9):548-56.

CAS Number: 1449236-96-7

Molecular Weight: 349.79

Compound Purity: 98.05

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: p97

• SKU: MEXHY-15714-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15714-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK