NOD2 (Internal) blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89233.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008]

Region Sequence: KFRFTDRERHCSPTD

Full Name: nucleotide binding oligomerization domain containing 2

• SKU: GTX89233-PEP-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX89233-PEP-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Human Gene ID: 64127