Product Description: Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils.
Applications: Cancer-programmed cell death
Formula: C14H12N4OS
References: [1]Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days
CAS Number: 147149-76-6
Molecular Weight: 284.34
Research Area: Others
Target: Antifolate