Product Description: NP-G2-044 is a potent, orally active fascin inhibitor, with an IC50 of ~2 μM. NP-G2-044 blocks tumor metastasis and increases antitumor immune response[1][2].
Applications: Cancer-programmed cell death
Formula: C21H16F3N3O2
References: [1]Han S, et al. Improving fascin inhibitors to block tumor cell migration and metastasis. Mol Oncol. 2016;10(7):966-980./[2]Vincent Chung, et al. Abstract C053: NP-G2-044, a novel fascin inhibitor, blocks tumor metastasis and increases antitumor immune response./[3]Fascin Inhibitor NP-G2-044.
CAS Number: 1807454-59-6
Molecular Weight: 399.37
Compound Purity: 99.76
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: β-catenin