NP118809, CAS 41332-24-5

Product Description: NP118809 is a potent N-type calcium channel blocker, with an IC50 of 0.11 μM; also less potently inhibits L-type calcium channel with an IC50 of 12.2 μM.

Applications: COVID-19-immunoregulation

Formula: C32H32N2O

References: [1]Zamponi GW, et al. Scaffold-based design and synthesis of potent N-type calcium channel blockers. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6467-72./[2]Pajouhesh H, et al. Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1378-83.

CAS Number: 41332-24-5

Molecular Weight: 460.61

Compound Purity: 98.73

Research Area: Cardiovascular Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Calcium Channel

• SKU: MEXHY-14462-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14462-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK