Product Description: NQ301 is an antithrombotic agent; inhibits collagen-challenged rabbit platelet aggregation with an IC50 of 10 mg/mL.
Applications: COVID-19-immunoregulation
Formula: C18H12ClNO3
References: [1]Jin YR, et al. An antithrombotic agent, NQ301, inhibits thromboxane A2 receptor and synthase activity in rabbit platelets. Basic Clin Pharmacol Toxicol. 2005 Sep;97(3):162-7./[2]Zhang YH, et al. Antiplatelet effect of 2-chloro-3-(4-acetophenyl)-amino-1,4-naphthoquinone (NQ301): a possible mechanism through inhibition of intracellular Ca2+ mobilization. Biol Pharm Bull. 2001 Jun;24(6):618-22.
CAS Number: 130089-98-4
Molecular Weight: 325.75
Compound Purity: 98.98
Research Area: Cardiovascular Disease
Solubility: DMSO : ≥ 7.14 mg/mL
Target: Thrombin