NSC 5844, CAS 140926-75-6

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N1,N2-bis(7-chloro-4-quinolinyl)-1,2-ethanediamine

Purity: ≥95%

Formula Markup: C20H16Cl2N4

Formula Weight: 383.3

CAS Number: 140926-75-6

Notes: NSC 5844 is a bis-quinoline with diverse biological activities.{41174,41175,41176} It inhibits the growth of P. falciparum strains that are sensitive (D-6) and resistant (W-2) to chloroquine (Item No. 14194) in vitro (IC50s = 17 and 27 nM, respectively) but lacks activity against P. berghei in vivo.{41174} NSC 5844 inhibits the growth of MDA-MB-468 and MCF-7 breast cancer cells with GI50 values of 7.35 and 14.80 μM, respectively.{41175} It also inhibits 24% of botulinum neurotoxin serotype A light chain (BoNT/A LC) metalloprotease activity at a concentration of 20 μM.{41176}

• SKU: CAY23443-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 23443-5
• Package Unit: 5 mg
• Quantity Unit: STK