NSC 697923, CAS 343351-67-7

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-[(4-methylphenyl)sulfonyl]-5-nitro-furan

Purity: ≥98%

Formula Markup: C11H9NO5S

Formula Weight: 267.3

CAS Number: 343351-67-7

Notes: NSC 697923 is a selective inhibitor of the E2 ubiquitin-conjugating enzyme Ubc13 when heterodimerized with Uev1A, blocking polyubiquitin chain formation at concentrations of 0.5 to 2 µM in vitro.{31222} It also inhibits NF-κB activation by PMA and other agonists, presumably through its effects on Ubc13.{31222} NSC 697923 blocks proliferation and induces apoptosis in diffuse large B cell lymphoma and neuroblastoma cells.{31222,31221} It has antitumor efficacy in vivo in neuroblastoma orthotopic xenografts, when given intraperitoneally.{31221}

• SKU: CAY15346-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 15346-5
• Package Unit: 5 mg
• Quantity Unit: STK