Product Description: NSC348884 is a nucleophosmin (NPM) inhibitor, it disrupts oligomer formation and induces apoptosis, inhibits cell proliferation with IC50s of 1.7-4.0 μM in distinct cancer cell lines. NSC348884 can be used for the research of cancer[1].
Applications: Cancer-programmed cell death
Formula: C38H40N10
References: [1]Qi W, et al. NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancercells. Oncogene. 2008 Jul 10;27(30):4210-20./[2]Lin Y, et al. Inhibition of nucleophosmin/B23 sensitizes ovarian cancer cells to antiprogrammed cell death protein-1 ligand therapy. 2022.
CAS Number: 81624-55-7
Molecular Weight: 636.79
Compound Purity: 98.0
Research Area: Cancer
Solubility: DMSO : ≥ 34 mg/mL
Target: Apoptosis