NTP42, CAS 2055599-51-2

Product Description: NTP42 is a thromboxane A2 (TXA2) receptor antagonist with an IC50 of 3.278 nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46619[1]. NTP42 can be used for the treatment of pulmonary arterial hypertension (PAH)[2].

Applications: Neuroscience-Neuromodulation

Formula: C25H23F2N3O5S

References: [1]B. Therese KINSELLA, et al. Thromboxane receptor antagonists. WO2016203314A1./[2]Eamon Mulvaney, et al. NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension.

CAS Number: 2055599-51-2

Molecular Weight: 515.53

Compound Purity: 98.02

Research Area: Cardiovascular Disease

Solubility: DMSO : 31.25 mg/mL (ultrasonic)

Target: Prostaglandin Receptor

• SKU: MEXHY-129851-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-129851-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK