Product Description: NVP-ACC789 is an inhibitor of human VEGFR-1, VEGFR-2 (mouse VEGFR-2), VEGFR-3 and PDGFR-β with IC50s of 0.38, 0.02 (0.23), 0.18, 1.4 μM, respectively.
Applications: Cancer-Kinase/protease
Formula: C21H17BrN4
References: [1]Tille JC, et al. Vascular endothelial growth factor (VEGF) receptor-2 antagonists inhibit VEGF- and basicfibroblast growth factor-induced angiogenesis in vivo and in vitro. J Pharmacol Exp Ther. 2001 Dec;299(3):1073-85.
CAS Number: 300842-64-2
Molecular Weight: 405.29
Compound Purity: 99.52
Research Area: Cancer
Solubility: DMSO : 25 mg/mL (ultrasonic)
Target: PDGFR;VEGFR