Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N-1H-indol-5-yl-benzamide
Purity: ≥98%
Formula Markup: C15H12N2O
Formula Weight: 236.3
CAS Number: 6019-39-2
Notes: Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC2 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts.{22003} The iPSCs developed using OAC2 retain the capacity for pluripotent differentiation, whether evaluated in vitro or in vivo.{22003}
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