Shelf life (days): 730.0
Formulation: A 10 µg/ml solution in acetonitrile
Formal Name: N-[[(3R)-5-chloro-3,4-dihydro-8-hydroxy-3-(methyl-13C)-1-oxo-1H-2-benzopyran-7-yl-1,3,4,4a,5,6,7,8,8a-13C9]carbonyl-13C]-L-phenylalanine-13C9
Purity: ≥98%
Formula Markup: [13C]20H18ClNO6
Formula Weight: 423.7
CAS Number: 911392-42-2
Notes: Ochratoxin A-13C20 (OTA-13C20) is intended for use as an internal standard for the quantification of OTA (Item No. 11439) by GC- or LC-MS. OTA is a mycotoxin that has been found in Penicillium and is an active metabolite of OTC (Item No. 20183).{31745,57301,21687} It is formed from OTC in vivo, however, OTC can also be formed from OTA by gut microbiota.{31745,51590} OTA (120 μg/kg) increases renal lipid peroxide levels and the number of apoptotic cells, as well as reduces renal superoxide dismutase (SOD) activity in rats.{57301} Topical application of OTA (80 μg/animal) induces DNA damage, cell cycle arrest at the G0/G1 phase, and apoptosis in mouse skin cells.{21687} It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. OTA has been found in food products and poultry feed.{59458,72197}
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