Product Description: TD139 is a synthetic galectin-3 inhibitor. TD139 has high affinity for galectin-3 with a Kd of 68 nM, a Kd of 0.22 μM for galectin-1, and a Kd of 38 μM for galectin-7[1].
Applications: COVID-19-immunoregulation
Formula: C28H30F2N6O8S
References: [1]Mackinnon AC, et al. Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med. 2012 Mar 1;185(5):537-46./[2]Volarevic V, et al. Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice. Hepatology. 2012 Jun;55(6):1954-64.
CAS Number: 1450824-22-2
Molecular Weight: 648.64
Compound Purity: 99.75
Research Area: Inflammation/Immunology
Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL
Target: Galectin