Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)-ethanone
Purity: ≥98%
Formula Markup: C15H14O4
Formula Weight: 258.26926
CAS Number: 487-49-0
Notes: Ononetin is a deoxybenzoin that has been found in O. spinosa and has diverse biological activities.{67041},{67042} It is an inhibitor of transient receptor potential melastatin 3 (TRPM3; IC50 = 0.3 µM for the mouse receptor).{67041} Ononetin scavenges DPPH (Item No. 14805), ABTS (Item No. 27317), and superoxide anion radicals in cell-free assays (IC50s = 57.4, 62.64, and 35.19 µM, respectively).{67042} It also inhibits mushroom tyrosinase activity with an IC50 value of 78.88 µM after 30 minutes. Ononetin (10 mg/kg) reverses heat hypersensitivity induced by complete Freund’s adjuvant in mice.{67043}