Product Description: Ozanimod (RPC-1063), a sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity selectively to S1P receptor subtypes 1 (S1P1) and 5 (S1P5). Ozanimod has modulate effect for hS1P1 and hS1P5 receptor with EC50s of 1.03 nM and 8.6 nM, respectively. Ozanimod can be used for the research of relapsing multiple sclerosis (MS)[1].
Applications: COVID-19-immunoregulation
Formula: C23H24N4O3
References: [1]Julie V Selkirk, et al. Deconstructing the Pharmacological Contribution of Sphingosine-1 Phosphate Receptors to Mouse Models of Multiple Sclerosis Using the Species Selectivity of Ozanimod, a Dual Modulator of Human Sphingosine 1-Phosphate Receptor Subtypes 1 and 5. J Pharmacol Exp Ther. 2021 Dec;379(3):386-399.
CAS Number: 1306760-87-1
Molecular Weight: 404.46
Compound Purity: 99.93
Research Area: Inflammation/Immunology; Neurological Disease
Solubility: DMSO : ≥ 29 mg/mL
Target: LPL Receptor
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