Shelf life (days): 1460.0
Formulation: A solid
Formal Name: sulfuric acid, mono(4-methylphenyl) ester, monopotassium salt
Purity: ≥95%
Formula Markup: C7H7O4S / K
Formula Weight: 226.29238
CAS Number: 91978-69-7
Notes: p-Cresol sulfate is a sulfate conjugate of the uremic toxin p-cresol, which is formed by bacterial fermentation of proteins in the large intestine.{45960,45961} p-Cresol sulfate increases migration and proliferation of isolated rat aortic vascular smooth muscle cells (VSMCs) when used at a concentration of 500 µM.{45962} It also increases the area of aortic atherosclerotic plaques in nephrectomized ApoE-/- mice fed a high-fat diet when administered at a dose of 100 mg/kg per day via the drinking water. Serum levels of total and free p-cresol sulfate are increased in patients with advanced stage chronic kidney disease and positively associated with vascular calcification.{45963}
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