Product Description: p-SCN-Bn-DOTA is a bifunctional chelating agent. p-SCN-Bn-DOTA can simultaneously chelate radionuclides and link monoclonal antibody for radioimmunoresearch of tumor[1][2].
Applications: Cancer-programmed cell death
Formula: C24H33N5O8S
References: [1]Vera DRB, et, al. Preclinical evaluation of (177)lu-nimotuzumab: a potential tool for radioimmunotherapy of epidermal growth factor receptor-overexpressing tumors. Cancer Biother Radiopharm. 2011 Jun;26(3):287-97./[2]Giannini G, et, al. Synthesis and preliminary in vitro evaluation of DOTA-Tenatumomab conjugates for theranostic applications in tenascin expressing tumors. Bioorg Med Chem. 2019 Aug 1;27(15):3248-3253.
CAS Number: 127985-74-4
Molecular Weight: 551.61
Compound Purity: 99.78
Research Area: Cancer
Solubility: DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Others