PA-8, CAS 878437-15-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-amino-5,8-dihydro-5-[3-methoxy-4-(2-propen-1-yloxy)phenyl]-pyrido[2,3-d]pyrimidine-4,7(3H,6H)-dione

Purity: ≥98%

Formula Markup: C17H18N4O4

Formula Weight: 342.4

CAS Number: 878437-15-1

Notes: A PAC1 receptor antagonist; selectively inhibits PACAP-induced CREB phosphorylation in CHO cells expressing the PAC1 receptor over CHO cells expressing VPAC1 or VPAC2 at 10 nM; inhibits PACAP-induced cAMP accumulation in CHO cells expressing the PAC1 receptor (IC50 = 2 nM); intrathecal administration reduces PACAP-induced transient aversive behaviors and mechanical allodynia in mice at 100 pmol/animal

• SKU: CAY42131-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42131-5
• Package Unit: 5 mg
• Quantity Unit: STK