PAK1 Antibody Polyclonal Antibody

Target Synonym: PAK;Pak1

Background: P21-activated kinase-1 (PAK1) is an enzyme associated with multiple metabolic networks and different types of cancers.PAK1 (RAC/CDC42-activated kinase 1) is the major oncogenic/ageing kinase, and its dysfunction extends the healthy lifespan of C. elegans by activating HSP16 gene. The p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1) expression appears to be predictive of prognosis in various solid tumors. PAK1 expression may be a predictive marker of overall survival and disease-specific survival in patients with solid tumors.p21-Activated kinase 1 (PAK1) has attracted much attention as a potential therapeutic target due to its central role in many oncogenic signaling pathways, its frequent dysregulation in cancers and neurological disorders, and its tractability as a target for small-molecule inhibition.

Immunogen: A synthetic peptide corresponding to the C-terminus of the Rat PAK1

Buffer: 0.2 μm filtered solution in PBS

Dilution: WB 1:500-1:1000;ICC/IF 1:1500-1:50000;IP 0.2-1 μL/mg of lysate

Calculated MW: 66 kDa

Observed MW: 72 kDa

• SKU: ELSAN100004P-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: AN100004P-100
• Package Unit: 100μL
• Quantity Unit: STK
• Reactivity: Rat (Rattus)
• Clonality: Polyclonal
• Application: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunocytochemistry
• Isotype: IgG
• Host: Rabbit
• Conjugate: Unconjugated