Target: parvalbumin
Conjugate: Biotin
Product Type: Monoclonal
Clone Number: C12
Immunogen: Synthetic peptide from the full length Rat Parvalbumin protein
Swiss-Prot: P02625
Purification: Protein A Purified
Storage Buffer: 136.36mM Ethanolamine, and 9.55mM Sodium Bicarbonate in 95.45% PBS
Concentration: 1mg/ml
Specificity: Detects 12 kDa.
Cellular Localization: Cytoplasmic vesicle membrane
Tissue Specificity: Retina. Expressed throughout the horizontal cells and/or terminals.
Scientific Background: Parvalbumin is involved in calcium signaling. Alterations in the function of parvalbumin-expressing neurons have been implicated in Alzheimer's, autism, schizophrenia, age-related cognitive defects and some forms of cancer (1).
References: 1. Cates. M.S., Teodoro M.L., Phillips G.N. (2002) Biophys J. 82(3): 1133-1146.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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