Paxalisib, CAS 1382979-44-3

Product Description: Paxalisib (GDC-0084) is a brain penetrant inhibitor of PI3K and mTOR, with Kis of 2 nM, 46 nM, 3 nM, 10 nM and 70 nM for PI3Kα PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively[1].

Applications: Cancer-Kinase/protease

Formula: C18H22N8O2

References: [1]Heffron TP, et al. Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR. ACS Med Chem Lett. 2016 Feb 16;7(4):351-6.

CAS Number: 1382979-44-3

Molecular Weight: 382.42

Compound Purity: 99.63

Research Area: Cancer

Solubility: DMSO : 7.69 mg/mL (ultrasonic;warming;heat to 60°C)

Target: mTOR;PI3K

• SKU: MEXHY-19962-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19962-25
• Package Unit: 25 mg
• Quantity Unit: STK