PCSK9-IN-10, CAS 368434-98-4

Product Description: PCSK9-IN-10 is a potent and orally active PCSK9 inhibitor with an IC50 value of 6.4 µM. PCSK9-IN-10 increases the expression of LDLR protein and decreases the expression of PCSK9. PCSK9-IN-10 reduces atherosclerosis progression. PCSK9-IN-10 has the potential for the research of hyperlipidemia[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C18H23N5O4

References: [1]Qiao MQ, et al. Structure-activity relationship and biological evaluation of xanthine derivatives as PCSK9 inhibitors for the treatment of atherosclerosis. Eur J Med Chem. 2022 Dec 26;247:115047.

CAS Number: 368434-98-4

Molecular Weight: 373.41

Compound Purity: 98.95

Research Area: Metabolic Disease; Cardiovascular Disease

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: PCSK9

• SKU: MEXHY-152221-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-152221-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK