PD1 blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89528.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Region Sequence: C-GELDFQWREKTPE

Full Name: programmed cell death 1

• SKU: GTX89528-PEP-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX89528-PEP-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Human Gene ID: 5133