Product Description: PD158780 is a potent EGFR family inhibitor with IC50s of 8 pM, 49, 52, 52 nM for EGFR, ErbB2, ErbB3, and ErbB4, respectively.
Applications: Cancer-Kinase/protease
Formula: C14H12BrN5
References: [1]Fry DW, et al. Biochemical and antiproliferative properties of 4-[ar(alk)ylamino]pyridopyrimidines, a new chemical class of potent and specific epidermal growth factor receptor tyrosine kinase inhibitor. Biochem Pharmacol. 1997 Oct 15;54(8):877-87.
CAS Number: 171179-06-9
Molecular Weight: 330.18
Compound Purity: 99.56
Research Area: Cancer
Solubility: DMSO : 16.67 mg/mL (ultrasonic)
Target: EGFR