Target Synonym: GAS;PDGFRA;CD140A;PDGFR-2;PDGFR2;GAS9;RHEPDGFRA;PDGF-RαAlpha platelet-derived growth factor receptor;Alpha-type platelet-derived growth factor receptor;CD_antigen: CD140a;CD140 antigen-like family member A;CD140a antigen;MGC74795;PDGF alpha chain;PDGFR 2;PDGFR alpha;PDGFRA/BCR fusion;PDGFR-alpha;PDGF-R-alpha;PGFRA;Platelet derived growth factor receptor;Platelet derived growth factor receptor 2;Platelet derived growth factor receptor alpha;Platelet derived growth factor receptor alpha polypeptide;Platelet-derived growth factor alpha receptor;Platelet-derived growth factor receptor 2;platelet-derived growth factor receptor A;Platelet-derived growth factor receptor alpha;platelet-derived growth factor receptor α;Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein
Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Immunogen: Recombinant Human PDGFRA / CD140a protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: WB 1:500-1:1000;
Calculated MW: 123 kDa
Observed MW: 123 kDa
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