PE Anti-Human CD158/KIR2DL1 Antibody(HP-MA4)

Target Synonym: CD158a;CD158g;CD158h;KIR2DL1;KIR2DS1;KIR2DS3;KIR2DS5

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/Kp98tD

Citation Link 2: Staining of normal human peripheral blood cells with APC Anti-Human CD56/NCAM Antibody[5.1H11] and PE Anti-Human CD158/KIR2DL1 Antibody[HP-MA4] (left) or PE Mouse IgG2b, κ Isotype Control (right). Cells in the lymphocytes gate were used for analysis.

Background: CD158 molecules, also known as KIRs (killer cell immunoglobulin-like receptors), are a family of transmembrane proteins with either two (KIR2D) or three (KIR3D) Ig-like extracellular domains. Some KIRs with long cytoplasmic domains contain ITIMs and posses inhibitory functions and others with short cytoplasmic region lack ITIM and have activation functions. 14 polymorphic KIR genes have been reported in humans. CD158 is mainly expressed on a subset of NK cells and a small population of CD8+ T cells. HLA-C is the ligand of CD158a/h.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1391D-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1391D-20
• Package Unit: 20 Tests
• Quantity Unit: PAK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Mouse IgG2b κ
• Human Gene ID: 3802
• Host: Mouse
• Conjugate: Conjugated, PE (Phycoerythrin)