PE-conjugated Anti-GDNF antibody(DMC498); IgG1 Chimeric mAb

PE-conjugated Anti-GDNF antibody(DMC498); IgG1 Chimeric mAb
SKU
DMADMC100498P-100
Packaging Unit
100 test
Manufacturer
DIMA Biotechnology

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Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein; a highly conserved neurotrophic factor; was shown to promote the survival and differentiation of dopaminergic neurons in culture; and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing. [provided by RefSeq; Aug 2016]

Description: PE-conjugated Anti-GDNF antibody(DMC498); IgG1 Chimeric mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid,PBS with 0.05% Proclin300, 288% BSA

Target: GDNF

Uniprot ID: P39905

Usage: Research use only

Clone ID: DMC498

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100
More Information
SKU DMADMC100498P-100
Manufacturer DIMA Biotechnology
Manufacturer SKU DMC100498P-100
Package Unit 100 test
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Flow Cytometry
Isotype Rabbit/Human Fc chimeric IgG1
Host Rabbit
Conjugate Conjugated, PE (Phycoerythrin)
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