Background: IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2, FGF-basic, and EGF.
Description: PE-conjugated Anti-IFNG antibody(1A2), IgG1 Chimeric mAb
Storage & Shipping: Store at 2°C-8°C for 6 months
Formulation & Reconstitution: Liquid,PBS with 0.05% Proclin300, 413% BSA
Target: IFNG
Uniprot ID: P01579
Usage: Research use only
Clone ID: 1A2
Purification: Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions: Flow Cyt 1:100