PE-conjugated Anti-IL4RA antibody(DMC284); IgG1 Chimeric mAb

Background: This gene encodes the alpha chain of the interleukin-4 receptor; a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein; and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy; a condition that can manifest itself as allergic rhinitis; sinusitus; asthma; or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

Description: PE-conjugated Anti-IL4RA antibody(DMC284); IgG1 Chimeric mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 210% BSA

Target: IL4RA

Uniprot ID: P24394

Usage: Research use only

Clone ID: DMC284

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100

• SKU: DMADMC100284P-100
• Manufacturer: DIMA Biotechnology
• Manufacturer SKU: DMC100284P-100
• Package Unit: 100 test
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rabbit/Human Fc chimeric IgG1
• Host: Rabbit
• Conjugate: Conjugated, PE (Phycoerythrin)