PE-conjugated Anti-PMEL antibody(DMC420); IgG1 Chimeric mAb

Background: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes; which are the melanin-producing organelles in melanocytes; and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

Description: PE-conjugated Anti-PMEL antibody(DMC420); IgG1 Chimeric mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 232% BSA

Target: PMEL

Uniprot ID: P40967

Usage: Research use only

Clone ID: DMC420

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100

• SKU: DMADMC100420P-100
• Manufacturer: DIMA Biotechnology
• Manufacturer SKU: DMC100420P-100
• Package Unit: 100 test
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rabbit/Human Fc chimeric IgG1
• Host: Rabbit
• Conjugate: Conjugated, PE (Phycoerythrin)