PE-conjugated Anti-TGFBR2 antibody(DMC467); IgG1 Chimeric mAb

Background: The protein encoded by this gene is a transmembrane protein that has a protein kinase domain; forms a heterodimeric complex with TGF-beta receptor type-1; and binds TGF-beta. This receptor:ligand complex phosphorylates proteins; which then enter the nucleus and regulate the transcription of genes related to cell proliferation; cell cycle arrest; wound healing; immunosuppression; and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome; Loeys-Deitz Aortic Aneurysm Syndrome; and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq; Aug 2017]

Description: PE-conjugated Anti-TGFBR2 antibody(DMC467); IgG1 Chimeric mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 261% BSA

Target: TGFBR2

Uniprot ID: P37173

Usage: Research use only

Clone ID: DMC467

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100

• SKU: DMADMC100467P-100
• Manufacturer: DIMA Biotechnology
• Manufacturer SKU: DMC100467P-100
• Package Unit: 100 test
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rabbit/Human Fc chimeric IgG1
• Host: Rabbit
• Conjugate: Conjugated, PE (Phycoerythrin)