PE/Cyanine5 Anti-Rat CD44H Antibody(OX-49)

Target Synonym: CD44sH-CAM;CD44H;Pgp-1

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/a54SqD

Citation Link 2: Rat splenocytes are stained with PE/Cyanine5 Anti-Rat CD44H Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.

Background: CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1225G-2X100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1225G-2X100
• Package Unit: 100 Testsx2
• Quantity Unit: PAK
• Reactivity: Rat (Rattus)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Mouse IgG2a κ
• Human Gene ID: 12505
• Host: Mouse
• Conjugate: Conjugated, PE-Cy5