PE/Cyanine7 Anti-Human CD146 Antibody(AA98)

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/l1dqD0

Citation Link 2: Staining of Hela cells with PE/Cyanine7 Anti-Human CD146 Antibody[AA98] (filled gray histogram) or PE/Cyanine7 Mouse IgG2a, κ Isotype Control (empty black histogram). Total viable cells were used for analysis.

Background: CD146 is a 118 kD integral transmembrane glycoprotein that is also known as MUC18, S-Endo, MCAM, and Mel-CAM (melanoma cell adhesion molecule). It belongs to the immunoglobulin superfamily. CD146 is expressed on melanoma cells, epithelial cells, endothelial cells, fibroblasts, activated T cells, multipotent mesenchymal stromal cells, and activated keratinocytes. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration. The ligand of CD146 remains to be identified.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1417H-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1417H-20
• Package Unit: 20 Tests
• Quantity Unit: PAK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Mouse IgG2a κ
• Human Gene ID: 4162
• Host: Mouse
• Conjugate: Conjugated, PE-Cy7