PE/Cyanine7 Anti-Mouse IL-17A Antibody(17F3)

Target Synonym: Ctla8;Il17a;Interleukin-17A

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/iDijL0

Citation Link 2: HEK293T cells transiently transfected with pcDNA3.1 plasmid encoding Mouse IL-17A gene are stained with PE/Cyanine7 Anti-Mouse IL-17A Antibody (filled gray histogram) or PE/Cyanine7 Mouse IgG1, κ Isotype Control (empty black histogram).

Background: The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-25A in vivo.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1272H-50
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1272H-50
• Package Unit: 50 Tests
• Quantity Unit: PAK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Mouse IgG1 κ
• Human Gene ID: 16171
• Host: Mouse
• Conjugate: Conjugated, PE-Cy7