PE/Elab Fluor® 594 Anti-Human CD20 Antibody(BCA/B20)

Target Synonym: B-lymphocyte antigen CD20;B-lymphocyte surface antigen B1;Bp35;CD20;Leukocyte surface antigen Leu-16;MS4A1;Membrane-spanning 4-domains subfamily A member 1

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/uayyaL

Citation Link 2: Human peripheral blood lymphocytes are stained with PE/Elab Fluor^® 594 Anti-Human CD20 Antibody[BCA/B20] (filled gray histogram) or PE/Elab Fluor^® 594 Mouse IgG2a, κ Isotype Control (empty black histogram).

Background: CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1045P-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1045P-100
• Package Unit: 100 Tests
• Quantity Unit: PAK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Mouse IgG2a κ
• Human Gene ID: 931
• Host: Mouse
• Conjugate: Conjugated, PE (Phycoerythrin), Elab Fluor594