PE/Elab Fluor® 594 Anti-Human CD45RA Antibody(HI100)

Target Synonym: CD45;L-CA;Ly-5;Ptprc;Receptor-type tyrosine-protein phosphatase C;T200

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/qXzbj5

Citation Link 2: Human peripheral blood lymphocytes are stained with APC Anti-Human CD45RO Antibody and PE/Elab Fluor^® 594 Anti-Human CD45RA Antibody (Left). Lymphocytes are stained with APC Anti-Human CD45RO Antibody and PE/Elab Fluor^® 594 Mouse IgG2b, κ Isotype Control (Right).

Background: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1052P-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1052P-100
• Package Unit: 100 Tests
• Quantity Unit: PAK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Mouse IgG2b κ
• Human Gene ID: 5788
• Host: Mouse
• Conjugate: Conjugated, PE (Phycoerythrin), Elab Fluor594