PE/Elab Fluor® 594 Anti-Human CD62L Antibody(DREG56)

Target Synonym: CD62L;CD62 antigen-like family member L;L-selectin;LAM-1;LECAM1;Lnhr;Ly-22;Ly22;Lymph node homing receptor;Sell

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/haae90

Citation Link 2: Human peripheral blood lymphocytes are stained with PE/Elab Fluor^® 594 Anti-Human CD62L Antibody[DREG56] (filled gray histogram) or PE/Elab Fluor^® 594 Mouse IgG1, κ Isotype Control (empty black histogram).

Background: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1051P-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1051P-100
• Package Unit: 100 Tests
• Quantity Unit: PAK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Mouse IgG1 κ
• Human Gene ID: 6402
• Host: Mouse
• Conjugate: Conjugated, PE (Phycoerythrin), Elab Fluor594