PE/Elab Fluor® 594 Anti-Mouse CD40 Antibody(FGK4.5/FGK45)

Target Synonym: B-cell surface antigen CD40;Bp50;CD40;CD40L receptor;Cd40;Tnfrsf5;Tumor necrosis factor receptor superfamily member 5

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/uDCWfT

Citation Link 2: C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD19 Antibody and PE/Elab Fluor^® 594 Anti-Mouse CD40 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD19 Antibody and PE/Elab Fluor^® 594 Rat IgG2a, κ Isotype Control (Right).

Background: CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1028P-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1028P-100
• Package Unit: 100 Tests
• Quantity Unit: PAK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rat IgG2a κ
• Human Gene ID: 21939
• Host: Rat
• Conjugate: Conjugated, PE (Phycoerythrin), Elab Fluor594