PE859, CAS 1402727-29-0

Product Description: PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66 and 1.2 μM, respectively.

Applications: Neuroscience-Neurodegeneration

Formula: C28H24N4O2

References: [1]Okuda M, et al. Design and synthesis of curcumin derivatives as tau and amyloid β dual aggregation inhibitors. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5024-5028./[2]Okuda M, et al. PE859, a novel tau aggregation inhibitor, reduces aggregated tau and prevents onset and progression of neural dysfunction in vivo. PLoS One. 2015 Feb 6;10(2):e0117511.

CAS Number: 1402727-29-0

Molecular Weight: 448.52

Compound Purity: 99.76

Research Area: Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Microtubule/Tubulin

• SKU: MEXHY-12662-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12662-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK