PerCP/Cyanine5.5 Anti-Mouse CD107a/LAMP-1 Antibody(1D4B)

Target Synonym: CD107 antigen-like family member Alysosomal membrane glycoprotein 1lysosome-associated membrane protein 1;LAMP-1;Lysosome-associated membrane glycoprotein 1

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/S44mbH

Citation Link 2: C57BL/6 murine abdominal macrophages elicited by starch broth are stained with PerCP/Cyanine5.5 Anti-Mouse CD107a Antibody (filled gray histogram) or PerCP/Cyanine5.5 Rat IgG2a,κ Isotype Control (empty black histogram).

Background: The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa.  It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1254J-50
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1254J-50
• Package Unit: 50 Tests
• Quantity Unit: PAK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rat IgG2a κ
• Human Gene ID: 16783
• Host: Rat
• Conjugate: Conjugated, PerCP-Cy5.5