PF-00446687 (free base), CAS 862281-92-3

Product Description: PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 ± 1 nM[1]. Pf-446687 is brain penetrant[2].

Formula: C28H36F2N2O2

References: [1]Lansdell MI, et al. Discovery of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans. J Med Chem. 2010 Apr 22;53(8):3183-97./[2]Modi ME, et al. Melanocortin Receptor Agonists Facilitate Oxytocin-Dependent Partner Preference Formation in the Prairie Vole. Neuropsychopharmacology. 2015 Jul;40(8):1856-65.

CAS Number: 862281-92-3

Molecular Weight: 470.59

Compound Purity: 99.78

Research Area: Endocrinology

Solubility: DMSO : 62.5 mg/mL (ultrasonic)

Target: Melanocortin Receptor

• SKU: MEXHY-10622-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10622-1
• Package Unit: 1 mg
• Quantity Unit: STK