PF-01247324, CAS 875051-72-2

Product Description: PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker with an IC50 of 196 nM for recombinant human Nav1.8 channel.

Applications: Neuroscience-Neuromodulation

Formula: C13H10Cl3N3O

References: [1]Payne CE, et al. A novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability. Br J Pharmacol. 2015 May;172(10):2654-70./[2]Shields SD, et al. Oral administration of PF-01247324, a subtype-selective Nav1.8 blocker, reverses cerebellar deficits in a mouse model of multiple sclerosis. PLoS One. 2015 Mar 6;10(3):e0119067.

CAS Number: 875051-72-2

Molecular Weight: 330.60

Compound Purity: 99.63

Research Area: Neurological Disease

Solubility: DMSO : ≥ 30 mg/mL

Target: Sodium Channel

• SKU: MEXHY-101383-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101383-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK