Product Description: PF-05180999 (PF-999) is a phosphodiesterase 2A (PDE2A) inhibitor, with an IC50 of 1.6 nM.
Applications: Neuroscience-Neuromodulation
Formula: C19H17F3N8
References: [1]Helal CJ, et al. Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate. J Med Chem. 2018 Feb 8;61(3):1001-1018.
CAS Number: 1394033-54-5
Molecular Weight: 414.39
Compound Purity: 99.97
Research Area: Neurological Disease
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Phosphodiesterase (PDE)