PF-06260933, CAS 1811510-56-1

Product Description: PF-06260933 is an orally active and highly selective inhibitor of MAP4K4 with IC50s of 3.7 and 160 nM for kinase and cell, respectively.

Applications: COVID-19-immunoregulation

Formula: C16H13ClN4

References: [1]Ammirati M, et al. Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment. ACS Med Chem Lett. 2015 Oct 6;6(11):1128-33./[2]Roth Flach RJ, et al. Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis. Nat Commun. 2015 Dec 21;6:8995.

CAS Number: 1811510-56-1

Molecular Weight: 296.75

Compound Purity: 99.67

Research Area: Inflammation/Immunology

Solubility: DMSO : 30 mg/mL (ultrasonic;warming)

Target: MAP4K

• SKU: MEXHY-19562-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19562-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK