PF-06426779, CAS 1817628-40-2

Product Description: PF-06426779 is a potent and selective inhibitor of interleukin?1 receptor associated kinase 4 (IRAK4), with an IC50 of 0.3 nM[1].

Applications: COVID-19-immunoregulation

Formula: C17H18FN3O4

References: [1]Lee KL, et, al. Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design. J Med Chem. 2017 Jul 13; 60(13): 5521-5542.

CAS Number: 1817628-40-2

Molecular Weight: 347.34

Compound Purity: 99.89

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: IRAK

• SKU: MEXHY-123854-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-123854-5
• Package Unit: 5 mg
• Quantity Unit: STK