PF-06679142, CAS 1467059-66-0

Product Description: PF-06679142 (Compound 10) is a potent, orally active AMPK activator with an EC50 of 22 nM against α1β1γ1-AMPK. PF-06679142 can be used for diabetic nephropathy research[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C20H17F2NO3

References: [1]Edmonds DJ, et al. Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK). J Med Chem. 2018 Mar 22;61(6):2372-2383.

CAS Number: 1467059-66-0

Molecular Weight: 357.35

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: AMPK

• SKU: MEXHY-120270-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-120270-1
• Package Unit: 1 mg
• Quantity Unit: STK